A Doctor can conduct an FAC test to determine if your affected joints are good candidates for A2M therapy. Since not all joints respond well to this therapy, having an FAC test to identify areas in which the specific proteins affected by A2M therapy are present. FAC stands for fibronectin-aggrecan G3 complex test, and it can offer a good estimate as to whether A2M therapy will be affective for your needs.

In some cases, regenerative therapy using stem cell injections may be a better fit. Often referred to as stem cell therapy, regenerative medicine is a state-of-the-art option for treating chronic pain by replacing, engineering, or regenerating cells, tissues or organs to stimulate the body’s own repair mechanisms. Using material directly from the patient’s own body in a minimally-invasive procedure, stem cell therapy provides the body with material it needs to heal quickly and thoroughly. Regenerative medicine typically has minimal risk and minimal recovery time.

A2M stands for Alpha 2 Macroglobulin. A2M therapy is a regenerative, biologic treatment used to treat degenerative conditions, such as arthritis, cartilage loss, or tissue damage at joints. A2M therapy utilizes injections to promote the body’s natural healing methods directly at the source of pain or injury.

Alpha 2 Macroglobulin is a protein naturally found in blood plasma. Its mechanism is to inhibit the enzymes that break down proteins (proteinases), such as Matrix Metalloproteinases (MMPs). It is these MMPs that are believed to be the main culprits that break down collagen within cartilage – therefore the main protagonist in arthritis development.

So in A2M therapy, Doctors introduce a natural, biological component whose job is to destroy the catalysts of tissue degeneration, with the goal being to support the natural restoration of the joint.

According to a study by Brown University & the National Institute of Health, “a joint injection of concentrated A2M provides cartilage protection in post-traumatic osteoarthritis by stopping the progression of arthritis.”

A2M therapy is the most-advanced method of stopping the advancement of joint degeneration and ending the chronic pain associated with it.