Regenerative Medicine is an advancing field of medicine that treats chronic pain by replacing, engineering, or regenerating cells, tissues, and organs to stimulate the body’s own repair mechanisms. Prolotherapy, Platelet-Rich Plasma (PRP), Stem Cell, and Alpha 2 Macroglobulin (A2M) injections are examples of regenerative medicine procedures that can be performed at Comprehensive Medical Care. These procedures are designed to decrease pain and return patients to normal function.

Some general conditions that can benefit from regenerative medicine include osteoarthritis, worn cartilage, degenerative nerve damage, and torn tendons, ligaments, cartilage and muscle. Specifically injuries and chronic pain conditions of the following parts have shown to benefit from regenerative medicine procedures:

Elbow: tennis elbow, golfer’s elbow, elbow osteoarthritis, UCL tears, tendon tears, arthritis

Feet/Ankle: ligament tears, osteoarthritis, tendon tears, Achilles issues, arthritis

Spine/Neck: degenerative disc disease, herniated discs, facet injections, spondylolysis, tendon tears, arthritis

Shoulder: rotator cuff injuries, labrum tears, overuse injuries, tendon tears, arthritis

Hips: bursitis, avascular necrosis, tendon tears, hip osteoarthritis

Knee: torn ACL, meniscus tear, degenerative problems of the knee, tendon tears, arthritis

Hands: carpal tunnel syndrome, thumb arthritis, TFCC tears, tendon tears, arthritis

Platelet-Rich Plasma Injections (PRP)

PRP refers to an injection of platelet-rich plasma used to treat pain and injuries.

What are platelets and how do they work?

Platelets are a specific type of cell within a person’s blood that can aid in naturally clotting and healing. Platelets, like other cells contain specific elements and healing functions such as alpha granules and PDGF that signal other healing factors and cells to flood to an area of pain or injury. Once there, the healing process can re-initiate.

What happens during a PRP injection procedure?

The patient’s blood is first drawn in our state-of-the-art medical facility. The blood is then put through a safe, sterile process that allows us to concentrate your platelets up to 106 times the normal limits. The platelets are then injected by a directly into the problem area under the guidance of ultrasound fluoroscopy which provides real-time imaging. The procedure is performed by a Physician specifically trained in Interventional and Regenerative Medicine.

How long does the procedure take?

The length of the procedure depends on the body part being treated. Most patients can expect to spend on average 45 minutes in the room during the procedure.

What can I expect following the procedure?

All patients heal and react differently following the procedure. It is common to feel injection site soreness for up to 48 hours following the procedure.

Is it safe/suggested to treat with a Physical/Occupational Therapist following the procedure?

Absolutely. All of the most recent studies point to a higher rate of success with multi-disciplinary approach to treatment. This leads to better patient outcomes and is one of the core values we focus on here at Comprehensive Medical Care.


Prolotherapy is a form of proliferation therapy used to heal orthopedic based injuries.

What does the Prolotherapy solution consist of?

Prolotherapy solutions contain natural substances such as saline, dextrose, and sarapin in conjunction with a numbing agent such as lidocaine.

What happens during a Prolothearpy procedure?

An injection of the solution is made in a specifically targeted area. Often this area is targeted through the guidance of ultrasound or video fluoroscopy to provide a precise injection site. The injection itself triggers the body’s healing response leading to the growth of new, healthy soft tissue such as ligaments and tendon fibers.

How long does the procedure take?

The procedure itself is roughly 45 minutes start to finish, depending on the body part the procedure is being performed on. Treatments are performed on average 3 to 6 times over the course of every 4 to 6 weeks, but some patients may only need 1 to 2 treatments. It is important to maintain your follow-up schedule so our Medical Providers can perform re-assessments at appropriate intervals to track the progress.

What can I expect following the procedure?

You should expect reduced pain and stiffness with increased ability to gain strength, function, and mobility of the joint.

Is there anything important I should know regarding the Prolotherapy procedure?

It is recommended to avoid the use of anti-inflammatory drugs such as ibuprofen and Motrin following the procedure as this could negatively impact the healing effect of the Prolotherapy. Please ask your Medical Provider for a list of medications that are deemed safe to use after the procedure.

Is it safe/suggested to treat with a Physical/Occupational Therapist following the procedure?

Prehabilitation and rehabilitation are always great ways to ensure we are targeting healing from all sides. Speak to your Medical Provider for more specifics in your case,

Stem Cell Injections

Stem cell injections are used to heal orthopedic injuries through the use of injecting the lab grown cartilage and tendon cells into specific areas of injury.

What are stem cells?

Stem cells are the body’s personalized repair kit. They are healing cells that are manipulated in a lab and injected into injured areas to stimulate tissue healing.

What can I expect from the procedure?

A stem cell injection is a non-surgical outpatient procedure. Patients may experience some minor discomfort for a short time following the treatment. It is an excellent alternative for patients concerned about long recovery times associated with surgical procedures.

How long does the procedure take?

Patients can expect to be in the facility for roughly 45 minutes on the procedure day, though times may vary based on injury site and type of injury.

Is it safe/suggested to treat with a Physical/Occupational Therapist following the procedure?

Our multi-specialty approach at Comprehensive Medical Care supports continued care through other channels such as Physical/Occupational Therapy.